If the setup fails with "None of the products that are addressed by this software update are installed on this computer. Click Cancel to exit setup." try the following: Start the setup and wait till the dialog appears, but don't click cancel. Now go to the root of the drive where VS2008 is installed. There should be a folder with a random name ("2a3c3425751ec881b40910" for example), copy the VS90-VCFeaturePack-Beta-KB945273-x86x64-ENU.msp file to a different location. Now cancel the setup. Now double-click the msp-file to start the patch manually. Make sure that you have at least 1 GB of free disk space on drive C.